Fmoc-PNA monomers

PNAs can be synthesized from the corresponding Fmoc-protected peptide nucleic acid monomers manually on solid phase or automated on peptide synthesizers using standard Fmoc chemistry. In continuous automated Fmoc-based solid phase synthesis of PNA-peptide oligomers, Fmoc/Bhoc-protected PNA monomers are preferred, since this allows for acid-catalyzed deprotection of all protecting groups plus simultaneous cleavage from the resin.

It is therefore not surprising, that our Fmoc/Bhoc-PNA monomers are a top seller at ASM with guaranteed high purity and solubility for all our monomers.

However, due to the somewhat reduced solubility of the Fmoc/Bhoc-protected PNA monomers, especially the Fmoc-PNA-G(Bhoc)-OH and the Fmoc-PNA-C(Bhoc)-OH which tend to precipitate when stored in solution, as an experienced PNA manufacturer, ASM also offers the corresponding Fmoc/Boc-protected PNA monomers on request.

For questions and orders contact us

Fmoc PNA Monomers

Structure

Common Name

Product No.

Quantity

EUR

Fmoc-PNA-T-OH
(Fmoc-T-Aeg-OH)
C26H26N4O7
MW: 506,51
CAS: 169396-92-3

5004027

1 g
10 g
25 g
>25 g

100
900
2.125
on request

Fmoc-PNA-C(Bhoc)-OH
(Fmoc-C(Bhoc)-Aeg-OH)
C39H35N5O8
MW: 701,72
CAS: 186046-81-1

5004528

1 g
10 g
25 g
>25 g

100
900
2.125
on request

Fmoc-PNA-A(Bhoc)-OH
(Fmoc-A(Bhoc)-Aeg-OH)
C40H35N7O7
MW: 725,75
CAS: 186046-82-2

5004529

1 g
10 g
25 g
>25 g

100
900
2.125
on request

Fmoc-PNA-G(Bhoc)-OH
(Fmoc-G(Bhoc)-Aeg-OH)
C40H35N7O8
MW: 741,75
CAS: 186046-83-3

5004530

1 g
10 g
25 g
>25 g

100
900
2.125
on request

Our prices are quoted ex-VAT. Any applicable tax and duties will be supported by the buyer. All other costs as for example freight and insurance are charged separately and depend on the order size and shipping address.
License Statement: PNA Monomers are made and sold pursuant to license under one or more of US Patents Nos. US 5,773,571, US 6,133,444, US 6,172,226, US 6,395,474, US 6,414,112, US 6,613,873, US 6,710,163 and US 6,713,602, or corresponding patent claims outside the US and are provided only for use in academic and commercial research and not for any commercial purposes. Information about licenses for commercial use of PNA Monomers is available from the PNA Inventor Group.e-mail: pnainventorgroup@yahoo.dk